Paper of Carina Dunlop on cell mechanosensing published as a Letter in Physical Review E

The paper “Cell-strain-energy costs of active control of contractility”, co-authored by Josephine Solowiej-Wedderburn (former Surrey PhD student and now a postdoc at icelab in Umea Sweden) and Carina Dunlop, has been published as a Letter in Physical Review E. The paper shows that there is a complex relationship between the work done by the cell and activity of its contractility network. In particular, up-regulating contractility need not be mechanically expensive in stiffer environments and where adhesion patterning is adjusted appropriately. The published version is available open access (link here). The image below is part of Figure 4 in the paper.