Paper of Anne Skeldon and Thalia Rodriguez Garcia published in PLOS Computational Biology

The paper “Method to determine whether sleep phenotypes are driven by endogenous circadian rhythms or environmental light by combining longitudinal data and personalised mathematical models“, co-authored by Anne Skeldon, Thalia Rodriguez Garcia, Sean Cleator, Ciro Della Monica (SSRC, Surrey), Kiran K G Ravindran (SSRC, Surrey), Victoria Revell (SSRC, Surrey), and Derk-Jan Dijk (SSRC, Surrey), has been published in PLOS Computational Biology (link to OA published version). This landmark paper emerged from a joint project between Surrey Mathematics, the Surrey Sleep Research Centre (SSRC), and the Dementia Research Institute. Sean Cleator was formerly a Post-doc at Surrey and is now a Data Scientist at Volant Autonomy in Bristol. The three main features of the paper are (1) they put together a new model for sleep-wake regulation; (2) they suggest a new measure for quantifying the effect of one day of light on our human biological clock, taking into account that the effect depends on both the intensity and time; and (3) they show that it is possible to create “personalised” models which match individual sleep timing and duration. The image below is Figure 3 from the paper.