Anne Skeldon visited the University of Oxford in the beginning of April (30 March to 1 April) to attend the Oxford Glymphatic and Brain Clearance Symposium, held at Keble College (website here). It was a very popular event on a hot topic in the field of Alzheimer’s disease (AD). A hallmark of AD is the build-up of sticky clumps of a protein (amyloid beta) in the brain known as plaques. In normal brains, amyloid beta is produced and cleared. But a small imbalance in the production and clearance leads to the accumulation of plaques over a period of approximately 20 years. The mechanisms of brain clearance are hotly debated. Anne has recently been modelling time series of amyloid beta in the blood and fitting it to data collected at the Surrey Sleep Research Centre in collaboration with Derk-Jan Dijk, Ciro della Monica and others. The attached diagram show their compartmental model structure.